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ea0003p296 | Thyroid | BES2002

Pyrimidine and purine metabolism in human leukocytes in autoimmunological thyroid diseases - RNA expression of some enzymes

Lewinski A , Brzezianska E , Karbownik M , Zasada K , Migdalska-Sek M , Pastuszak-Lewandoska D

Increased blood activities of some enzymes, participating in pyrimidine and purine metabolism, were found in blood fractions of patients suffering from autoimmunological thyroid diseases (AITD), i.e., Graves' or Hashimoto's disease. The aim of the study was to estimate the expression of RNA specific for the enzymes in question. An approval of the Ethical Committee of the Medical University of Lodz has been obtained. The expression of the following enzymes was estimated in huma...